Cellular Milieu Imparts Distinct Pathological α-Synuclein Strains in α-Synucleinopathies

In Lewy body (LB) diseases, including Parkinson’s disease (PD), without and with dementia (PDD), dementia with Lewy bodies (DLB) and Alzheimer’s disease (AD) patients with LB co-pathology(1), α-synuclein (α-Syn) aggregates in neurons as LBs and Lewy neurites (LNs)(2), while in multiple system atroph...

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Vydáno v:Nature
Hlavní autoři: Peng, Chao, Gathagan, Ronald J., Covell, Dustin J., Medellin, Coraima, Stieber, Anna, Robinson, John L., Zhang, Bin, Pitkin, Rose M., Olufemi, Modupe F., Luk, Kelvin C., Trojanowski, John Q., Lee, Virginia M.-Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970994/
https://ncbi.nlm.nih.gov/pubmed/29743672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0104-4
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