Convergence of Heat Shock Protein 90 with Ubiquitin in Filamentous α-Synuclein Inclusions of α-Synucleinopathies

Heat shock proteins (Hsps) facilitate refolding of denatured polypeptides, but there is limited understanding about their roles in neurodegenerative diseases characterized by misfolded proteins. Because Parkinson’s disease (PD), dementia with Lewy bodies, and multiple system atrophy are α-synucleino...

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Bibliografiske detaljer
Main Authors: Uryu, Kunihiro, Richter-Landsberg, Christiane, Welch, William, Sun, Eveline, Goldbaum, Olaf, Norris, Erin H., Pham, Chi-Tuan, Yazawa, Ikuru, Hilburger, Kristen, Micsenyi, Matthew, Giasson, Benoit I., Bonini, Nancy M., Lee, Virginia M.-Y., Trojanowski, John Q.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2006
Fag:
Original Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606542/
https://ncbi.nlm.nih.gov/pubmed/16507910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050770
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