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Reduced Level of CD44 and Hyaluronan Associated with Unfavorable Prognosis in Clinical Stage I Cutaneous Melanoma

The cell surface glycoprotein CD44 and its ligand, hyaluronan (HA), enhance growth and metastatic capacity of melanoma cells in vitro, but their clinical significance in primary cutaneous melanoma is still unclear. Therefore, we studied whether the levels of CD44 and HA associate with disease progre...

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Detalhes bibliográficos
Main Authors: Karjalainen, Jari M., Tammi, Raija H., Tammi, Markku I., Eskelinen, Matti J., Ågren, Ulla M., Parkkinen, Jyrki J., Alhava, Esko M., Kosma, Veli-Matti
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885706/
https://ncbi.nlm.nih.gov/pubmed/10980134
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