Reduced Level of CD44 and Hyaluronan Associated with Unfavorable Prognosis in Clinical Stage I Cutaneous Melanoma

The cell surface glycoprotein CD44 and its ligand, hyaluronan (HA), enhance growth and metastatic capacity of melanoma cells in vitro, but their clinical significance in primary cutaneous melanoma is still unclear. Therefore, we studied whether the levels of CD44 and HA associate with disease progre...

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Autors principals: Karjalainen, Jari M., Tammi, Raija H., Tammi, Markku I., Eskelinen, Matti J., Ågren, Ulla M., Parkkinen, Jyrki J., Alhava, Esko M., Kosma, Veli-Matti
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2000
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885706/
https://ncbi.nlm.nih.gov/pubmed/10980134
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