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Reduced Level of CD44 and Hyaluronan Associated with Unfavorable Prognosis in Clinical Stage I Cutaneous Melanoma

The cell surface glycoprotein CD44 and its ligand, hyaluronan (HA), enhance growth and metastatic capacity of melanoma cells in vitro, but their clinical significance in primary cutaneous melanoma is still unclear. Therefore, we studied whether the levels of CD44 and HA associate with disease progre...

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Auteurs principaux: Karjalainen, Jari M., Tammi, Raija H., Tammi, Markku I., Eskelinen, Matti J., Ågren, Ulla M., Parkkinen, Jyrki J., Alhava, Esko M., Kosma, Veli-Matti
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885706/
https://ncbi.nlm.nih.gov/pubmed/10980134
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