Hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in the accumulation of hyaluronan in endometrioid endometrial carcinoma

BACKGROUND: Hyaluronan accumulation correlates with the degree of malignancy in many solid tumor types, including malignant endometrial carcinomas. To elucidate the mechanism of hyaluronan accumulation, we examined the expression levels of the hyaluronan synthases (HAS1, HAS2 and HAS3) and hyaluroni...

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Detalhes bibliográficos
Main Authors: Nykopp, Timo K, Rilla, Kirsi, Tammi, Markku I, Tammi, Raija H, Sironen, Reijo, Hämäläinen, Kirsi, Kosma, Veli-Matti, Heinonen, Seppo, Anttila, Maarit
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956733/
https://ncbi.nlm.nih.gov/pubmed/20875124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-512
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