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Hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in the accumulation of hyaluronan in endometrioid endometrial carcinoma

BACKGROUND: Hyaluronan accumulation correlates with the degree of malignancy in many solid tumor types, including malignant endometrial carcinomas. To elucidate the mechanism of hyaluronan accumulation, we examined the expression levels of the hyaluronan synthases (HAS1, HAS2 and HAS3) and hyaluroni...

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Hlavní autoři: Nykopp, Timo K, Rilla, Kirsi, Tammi, Markku I, Tammi, Raija H, Sironen, Reijo, Hämäläinen, Kirsi, Kosma, Veli-Matti, Heinonen, Seppo, Anttila, Maarit
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956733/
https://ncbi.nlm.nih.gov/pubmed/20875124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-512
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