Expression of Hyaluronan Synthases (HAS1–3) and Hyaluronidases (HYAL1–2) in Serous Ovarian Carcinomas: Inverse Correlation between HYAL1 and Hyaluronan Content

BACKGROUND: Hyaluronan, a tumor promoting extracellular matrix polysaccharide, is elevated in malignant epithelial ovarian tumors, and associates with an unfavorable prognosis. To explore possible contributors to the accumulation of hyaluronan, we examined the expression of hyaluronan synthases (HAS...

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Detalhes bibliográficos
Main Authors: Nykopp, Timo K, Rilla, Kirsi, Sironen, Reijo, Tammi, Markku I, Tammi, Raija H, Hämäläinen, Kirsi, Heikkinen, Anna-Mari, Komulainen, Marja, Kosma, Veli-Matti, Anttila, Maarit
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689240/
https://ncbi.nlm.nih.gov/pubmed/19435493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-143
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