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The impact of CYP2C8 polymorphism and grapefruit juice on the pharmacokinetics of repaglinide

AIMS: The primary aim of the study was to investigate the possible effect of the CYP2C8 3 allele and of grapefruit juice on the pharmacokinetics of repaglinide. Furthermore, the impact of a single dose of grapefruit juice on the pharmacokinetics of repaglinide in relation to dose. METHODS: Thirty-si...

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Detalhes bibliográficos
Main Authors: Bidstrup, Tanja Busk, Damkier, Per, Olsen, Anette Kristensen, Ekblom, Marianne, Karlsson, Anders, Brøsen, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884987/
https://ncbi.nlm.nih.gov/pubmed/16390351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02516.x
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