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Effects of grapefruit juice on pharmacokinetics of atorvastatin and pravastatin in Japanese

AIMS: To investigate the effects of repeated grapefruit juice (GFJ) intake on the pharmacokinetics of atorvastatin and pravastatin in Japanese subjects. METHODS: Two randomized, two-way crossover studies were performed. GFJ or water was given to two groups of 10 subjects each three times daily for 2...

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Detalhes bibliográficos
Main Authors: Fukazawa, Ichiro, Uchida, Naoki, Uchida, Eiji, Yasuhara, Hajime
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884469/
https://ncbi.nlm.nih.gov/pubmed/15025743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.02030.x
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