Effects of grapefruit juice on the pharmacokinetics of pitavastatin and atorvastatin

AIMS: To compare the effects of grapefruit juice (GFJ) on the pharmacokinetics of pitavastatin and atorvastatin. METHODS: In a randomized, four-phase crossover study, eight healthy subjects consumed either GFJ or water t.i.d. for 4 days in each trial. On each final day, a single dose of 4 mg pitavas...

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Hlavní autoři: Ando, Hitoshi, Tsuruoka, Shuichi, Yanagihara, Hayato, Sugimoto, Koh-ichi, Miyata, Masaaki, Yamazoe, Yasushi, Takamura, Toshinari, Kaneko, Shuichi, Fujimura, Akio
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2005
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884940/
https://ncbi.nlm.nih.gov/pubmed/16236039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02462.x
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