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Renal dehydropeptidase-I stability of LJC 10,627, a new carbapenem antibiotic.

LJC 10,627 is a new parenteral carbapenem antibiotic. LJC 10,627 stability against human renal dehydropeptidase-I was compared with that of imipenem. Hydrolysis of this compound was not detectable by spectrophotometrical assay. Even after a 2-h incubation of antibiotics with this enzyme at 30 degree...

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Bibliografiset tiedot
Julkaisussa:Antimicrob Agents Chemother
Päätekijät: Hikida, M, Kawashima, K, Nishiki, K, Furukawa, Y, Nishizawa, K, Saito, I, Kuwao, S
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 1992
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188463/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1605616/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.2.481
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