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Renal dehydropeptidase-I stability of LJC 10,627, a new carbapenem antibiotic.

LJC 10,627 is a new parenteral carbapenem antibiotic. LJC 10,627 stability against human renal dehydropeptidase-I was compared with that of imipenem. Hydrolysis of this compound was not detectable by spectrophotometrical assay. Even after a 2-h incubation of antibiotics with this enzyme at 30 degree...

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Detalhes bibliográficos
Main Authors: Hikida, M, Kawashima, K, Nishiki, K, Furukawa, Y, Nishizawa, K, Saito, I, Kuwao, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC188463/
https://ncbi.nlm.nih.gov/pubmed/1605616
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