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Renal dehydropeptidase-I stability of LJC 10,627, a new carbapenem antibiotic.

LJC 10,627 is a new parenteral carbapenem antibiotic. LJC 10,627 stability against human renal dehydropeptidase-I was compared with that of imipenem. Hydrolysis of this compound was not detectable by spectrophotometrical assay. Even after a 2-h incubation of antibiotics with this enzyme at 30 degree...

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Библиографические подробности
Опубликовано в::Antimicrob Agents Chemother
Главные авторы: Hikida, M, Kawashima, K, Nishiki, K, Furukawa, Y, Nishizawa, K, Saito, I, Kuwao, S
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1992
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188463/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1605616/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.2.481
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