Antimicrobial activity of MDL 62,873, a semisynthetic derivative of teicoplanin, in vitro and in experimental infections.

MDL 62,873 is an amide derivative of teicoplanin A2-2. Like those of natural glycopeptides, its antibacterial activity is mediated by inhibition of cell wall peptidoglycan synthesis. Against streptococci and enterococci, the in vitro activity of MDL 62,873 was similar to that of teicoplanin and grea...

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Bibliographic Details
Main Authors: Berti, M, Candiani, G, Borgonovi, M, Landini, P, Ripamonti, F, Scotti, R, Cavenaghi, L, Denaro, M, Goldstein, B P
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC188455/
https://ncbi.nlm.nih.gov/pubmed/1534978
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