Antimicrobial activity of MDL 62,873, a semisynthetic derivative of teicoplanin, in vitro and in experimental infections.

MDL 62,873 is an amide derivative of teicoplanin A2-2. Like those of natural glycopeptides, its antibacterial activity is mediated by inhibition of cell wall peptidoglycan synthesis. Against streptococci and enterococci, the in vitro activity of MDL 62,873 was similar to that of teicoplanin and grea...

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Publicat a:	Antimicrob Agents Chemother
Autors principals:	Berti, M, Candiani, G, Borgonovi, M, Landini, P, Ripamonti, F, Scotti, R, Cavenaghi, L, Denaro, M, Goldstein, B P
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1992
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188455/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1534978/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.2.446
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