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Pharmacokinetics of MDL 63,246, a new semisynthetic glycopeptide antibiotic, in the rat.

Following intravenous administration in the rat, the concentration of MDL 63,246 in plasma was high and long-lasting. Concentrations fell with an apparent three-exponential decay. MDL 63,246 was distributed in a high volume and was cleared quite slowly. The pharmacokinetics of MDL 63,246 in the rat...

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Autori principali: Borgonovi, M, Cavenaghi, L A, Borghi, A, Galimberti, M, Kaltofen, P, Merati, R, Coutant, J E
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC162909/
https://ncbi.nlm.nih.gov/pubmed/8619562
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