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In vitro antiviral activity of the 6-substituted 2-(3',4'-dichlorophenoxy)-2H-pyrano[2,3-b]pyridines MDL 20,610, MDL 20,646, and MDL 20,957.

The 6-substituted 2-(3',4'-dichlorophenoxy)-2H-pyrano[2,3-b]pyridines MDL 20,610 (6-SO2CH3), MDL 20,646 (6-Br), and MDL 20,957 (6-Cl) are potent antirhinovirus compounds with median plaque 50% inhibitory concentrations (IC1/2s) of 0.03, 0.006, and 0.006 micrograms/ml, respectively, against the 32 se...

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Publicado no:Antimicrob Agents Chemother
Principais autores: Kenny, M T, Dulworth, J K, Bargar, T M, Torney, H L, Graham, M C, Manelli, A M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1986
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180594/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3593475/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.30.3.516
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