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Blood–brain barrier transport of morphine in patients with severe brain trauma
AIMS: In experimental studies, morphine pharmacokinetics is different in the brain compared with other tissues due to the properties of the blood–brain barrier, including action of efflux pumps. It was hypothesized in this clinical study that active efflux of morphine occurs also in human brain, and...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1884477/ https://ncbi.nlm.nih.gov/pubmed/15025740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.02032.x |
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