Leukotriene C(4) synthase polymorphisms and responsiveness to leukotriene antagonists in asthma

AIM: Cysteinyl leukotrienes are important pro-inflammatory mediators in the pathogenesis of asthma, while leukotriene C(4) synthase is a key enzyme in their biosynthesis. Our aim is to evaluate whether responsiveness to leukotriene receptor antagonists was determined by expression of the variant (C)...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Currie, Graeme P, Lima, John J, Sylvester, Jim E, Lee, Daniel K C, Cockburn, Wendy J R, Lipworth, Brian J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2003
Konular:
Pharmacogenetics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884371/
https://ncbi.nlm.nih.gov/pubmed/12968987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01952.x
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