The arginine-16 β(2)-adrenoceptor polymorphism predisposes to bronchoprotective subsensitivity in patients treated with formoterol and salmeterol

AIMS: The relationship between β(2)-adrenoceptor polymorphisms and bronchoprotective response with long-acting β(2)-adrenoceptor agonists is unknown. METHODS: We retrospectively analysed data from six placebo-controlled randomized studies in corticosteroid treated asthmatics where formoterol or salm...

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Hlavní autoři: Lee, Daniel K C, Currie, Graeme P, Hall, Ian P, Lima, John J, Lipworth, Brian J
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2004
Témata:
Pharmacogenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884417/
https://ncbi.nlm.nih.gov/pubmed/14678342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01955.x
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