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Cross tolerance to salbutamol occurs independently of ß(2) adrenoceptor genotype-16 in asthmatic patients receiving regular formoterol or salmeterol

Background: The development of tolerance following the use of long acting ß(2) agonists in asthmatic patients with either the homozygous arginine (Arg-16) or glycine (Gly-16) genotypes is poorly documented, especially in relation to the acute reliever response to salbutamol in constricted airways. A...

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Detalhes bibliográficos
Main Authors: Lee, D, Jackson, C, Bates, C, Lipworth, B
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1747085/
https://ncbi.nlm.nih.gov/pubmed/15282385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2003.019059
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