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Leukotriene C(4) synthase polymorphisms and responsiveness to leukotriene antagonists in asthma
AIM: Cysteinyl leukotrienes are important pro-inflammatory mediators in the pathogenesis of asthma, while leukotriene C(4) synthase is a key enzyme in their biosynthesis. Our aim is to evaluate whether responsiveness to leukotriene receptor antagonists was determined by expression of the variant (C)...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1884371/ https://ncbi.nlm.nih.gov/pubmed/12968987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01952.x |
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