Effect of rifampicin on the pharmacokinetics and pharmacodynamics of nateglinide in healthy subjects

AIMS: Our aim was to investigate the effects of rifampicin on the pharmacokinetics and pharmacodynamics of nateglinide, a novel short-acting antidiabetic drug. METHODS: In a randomized crossover study with two phases, 10 healthy volunteers took 600 mg rifampicin or placebo orally once daily for 5 da...

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Detaylı Bibliyografya
Asıl Yazarlar: Niemi, Mikko, Backman, Janne T, Neuvonen, Mikko, Neuvonen, Pertti J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2003
Konular:
Drug Interactions
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884366/
https://ncbi.nlm.nih.gov/pubmed/12968988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01884.x
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