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Lack of pharmacokinetic interaction between retigabine and phenobarbitone at steady-state in healthy subjects

AIMS: To evaluate potential pharmacokinetic interactions between phenobarbitone and retigabine, a new antiepileptic drug. METHODS: Fifteen healthy men received 200 mg of retigabine on day 1. On days 4–32, phenobarbitone 90 mg was administered at 22.00 h. On days 26–32, increasing doses of retigabine...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ferron, Geraldine M, Patat, Alain, Parks, Virginia, Rolan, Paul, Troy, Steven M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884339/
https://ncbi.nlm.nih.gov/pubmed/12848774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01825.x
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