Lack of effect of ketoconazole on the pharmacokinetics of rosuvastatin in healthy subjects

AIMS: To examine in vivo the effect of ketoconazole on the pharmacokinetics of rosuvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. METHODS: This was a randomized, double-blind, two-way crossover, placebo-controlled trial. Healthy male volunteers (n = 14) received ket...

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Detalhes bibliográficos
Main Authors: Cooper, Kelvin J, Martin, Paul D, Dane, Aaron L, Warwick, Mike J, Raza, Ali, Schneck, Dennis W
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Drug Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884190/
https://ncbi.nlm.nih.gov/pubmed/12534645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01720.x
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