Lack of a pharmacokinetic interaction between steady-state roflumilast and single-dose midazolam in healthy subjects

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: Cytochrome P450 (CYP) 3A4 plays a prominent role in the metabolism of many drugs, which in turn implies, that changes in the activity of this enzyme caused by, for example, co-administered drugs, might result in clinically significant drug interactions. Rofl...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nassr, Nassr, Lahu, Gezim, von Richter, Oliver, Reutter, Felix, Knoerzer, Dietrich, Zech, Karl, Erb, Katharina A, Schug, Barbara, Blume, Henning, Hermann, Robert
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Science Inc 2007
Gaiak:
Short Reports
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1859981/
https://ncbi.nlm.nih.gov/pubmed/16981901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02762.x
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