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Pharmacokinetics of oral betaine in healthy subjects and patients with homocystinuria

AIMS: Large oral doses of betaine have proved effective in lowering plasma homocysteine in severe hyperhomocysteinaemia. The pharmacokinetic characteristics and metabolism of betaine in humans have not been assessed and drug monitoring for betaine therapy is not available. We studied the pharmacokin...

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Bibliografiske detaljer
Main Authors: Schwahn, Bernd C, Hafner, Dieter, Hohlfeld, Thomas, Balkenhol, Nina, Laryea, Maurice D, Wendel, Udo
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2003
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884185/
https://ncbi.nlm.nih.gov/pubmed/12534635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01717.x
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