Pharmacokinetics of oral betaine in healthy subjects and patients with homocystinuria

AIMS: Large oral doses of betaine have proved effective in lowering plasma homocysteine in severe hyperhomocysteinaemia. The pharmacokinetic characteristics and metabolism of betaine in humans have not been assessed and drug monitoring for betaine therapy is not available. We studied the pharmacokin...

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Detalhes bibliográficos
Main Authors: Schwahn, Bernd C, Hafner, Dieter, Hohlfeld, Thomas, Balkenhol, Nina, Laryea, Maurice D, Wendel, Udo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884185/
https://ncbi.nlm.nih.gov/pubmed/12534635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01717.x
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