Inhibition of cap (m7GpppXm)-dependent endonuclease of influenza virus by 4-substituted 2,4-dioxobutanoic acid compounds.

Synthesis of influenza virus mRNA is primed by capped and methylated (cap 1, m7GpppXm) RNAs which the virus derives by endonucleolytic cleavage from RNA polymerase II transcripts in host cells. The conserved nature of the endonucleolytic processing provides a unique target for the development of ant...

Volledige beschrijving

Bibliografische gegevens

Gepubliceerd in:	Antimicrob Agents Chemother
Hoofdauteurs:	Tomassini, J, Selnick, H, Davies, M E, Armstrong, M E, Baldwin, J, Bourgeois, M, Hastings, J, Hazuda, D, Lewis, J, McClements, W
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 1994
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188292/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7695269/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.12.2827
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!