Inhibition of cap (m7GpppXm)-dependent endonuclease of influenza virus by 4-substituted 2,4-dioxobutanoic acid compounds.

Synthesis of influenza virus mRNA is primed by capped and methylated (cap 1, m7GpppXm) RNAs which the virus derives by endonucleolytic cleavage from RNA polymerase II transcripts in host cells. The conserved nature of the endonucleolytic processing provides a unique target for the development of ant...

Descripció completa

Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Tomassini, J, Selnick, H, Davies, M E, Armstrong, M E, Baldwin, J, Bourgeois, M, Hastings, J, Hazuda, D, Lewis, J, McClements, W
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1994
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188292/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7695269/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.12.2827
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!