Identification of highly potent and selective inhibitors of Toxoplasma gondii dihydrofolate reductase.
Toxoplasma gondii RH was obtained in high yield from culture in RPMI medium on a line of Chinese hamster ovary cells lacking dihydrofolate reductase activity (ATCC 3952 dhfr-; American Type Culture Collection). Dihydrofolate reductase preparations from harvested organisms had specific activities of...
保存先:
| 出版年: | Antimicrob Agents Chemother |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
1993
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188092/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8239605/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.9.1914 |
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