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Comprehensive mutant enzyme and viral variant assessment of human immunodeficiency virus type 1 reverse transcriptase resistance to nonnucleoside inhibitors.

The nonnucleoside reverse transcriptase (RT) inhibitors comprise a class of structurally diverse compounds that are functionally related and specific for the human immunodeficiency virus type 1 RT. Viral variants resistant to these compounds arise readily in cell culture and in treated, infected hum...

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Hlavní autoři: Byrnes, V W, Sardana, V V, Schleif, W A, Condra, J H, Waterbury, J A, Wolfgang, J A, Long, W J, Schneider, C L, Schlabach, A J, Wolanski, B S
Médium: Artigo
Jazyk:Inglês
Vydáno: 1993
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC188022/
https://ncbi.nlm.nih.gov/pubmed/7692811
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