Comprehensive mutant enzyme and viral variant assessment of human immunodeficiency virus type 1 reverse transcriptase resistance to nonnucleoside inhibitors.

The nonnucleoside reverse transcriptase (RT) inhibitors comprise a class of structurally diverse compounds that are functionally related and specific for the human immunodeficiency virus type 1 RT. Viral variants resistant to these compounds arise readily in cell culture and in treated, infected hum...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Byrnes, V W, Sardana, V V, Schleif, W A, Condra, J H, Waterbury, J A, Wolfgang, J A, Long, W J, Schneider, C L, Schlabach, A J, Wolanski, B S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188022/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7692811/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.8.1576
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