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Coarse-Grained Strategy for Modeling Protein Stability in Concentrated Solutions. III: Directional Protein Interactions

We extend our coarse-grained modeling strategy described in parts I and II of this investigation to account for nonuniform spatial distributions of hydrophobic residues on the solvent-exposed surfaces of native proteins. Within this framework, we explore how patchy surfaces can influence the solvent...

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Библиографические подробности
Главные авторы: Cheung, Jason K., Shen, Vincent K., Errington, Jeffrey R., Truskett, Thomas M.
Формат: Artigo
Язык:Inglês
Опубликовано: Biophysical Society 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877792/
https://ncbi.nlm.nih.gov/pubmed/17400697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.099085
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