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The Effects of Force Inhibition by Sodium Vanadate on Cross-Bridge Binding, Force Redevelopment, and Ca(2+) Activation in Cardiac Muscle

Strongly bound, force-generating myosin cross-bridges play an important role as allosteric activators of cardiac thin filaments. Sodium vanadate (Vi) is a phosphate analog that inhibits force by preventing cross-bridge transition into force-producing states. This study characterizes the mechanical s...

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Main Authors: Martyn, D. A., Smith, L., Kreutziger, K. L., Xu, S., Yu, L. C., Regnier, M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Biophysical Society 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877787/
https://ncbi.nlm.nih.gov/pubmed/17400698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.096768
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