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Effect of Ca(2+) binding properties of troponin C on rate of skeletal muscle force redevelopment

To investigate effects of altering troponin (Tn)C Ca(2+) binding properties on rate of skeletal muscle contraction, we generated three mutant TnCs with increased or decreased Ca(2+) sensitivities. Ca(2+) binding properties of the regulatory domain of TnC within the Tn complex were characterized by f...

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Huvudupphovsmän: Lee, Ryan S., Tikunova, Svetlana B., Kline, Kristopher P., Zot, Henry G., Hasbun, Javier E., Minh, Nguyen Van, Swartz, Darl R., Rall, Jack A., Davis, Jonathan P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980305/
https://ncbi.nlm.nih.gov/pubmed/20702687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00491.2009
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