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Cross-Bridge versus Thin Filament Contributions to the Level and Rate of Force Development in Cardiac Muscle

In striated muscle thin filament activation is initiated by Ca(2+) binding to troponin C and augmented by strong myosin binding to actin (cross-bridge formation). Several lines of evidence have led us to hypothesize that thin filament properties may limit the level and rate of force development in c...

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Detalhes bibliográficos
Main Authors: Regnier, M., Martin, H., Barsotti, R. J., Rivera, A. J., Martyn, D. A., Clemmens, E.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304586/
https://ncbi.nlm.nih.gov/pubmed/15345560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.039123
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