Diarylsulfones, a new chemical class of nonnucleoside antiviral inhibitors of human immunodeficiency virus type 1 reverse transcriptase.

A series of variously substituted diarylsulfones and related derivatives were found to prevent human immunodeficiency virus type 1 (HIV-1) replication and HIV-1-induced cell killing in vitro. One of the more potent derivatives, 2-nitrophenyl phenyl sulfone (NPPS), completely protected human CEM-SS l...

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Autores principales: McMahon, J B, Gulakowski, R J, Weislow, O S, Schultz, R J, Narayanan, V L, Clanton, D J, Pedemonte, R, Wassmundt, F W, Buckheit, R W, Decker, W D
Formato: Artigo
Lenguaje:Inglês
Publicado: 1993
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC187752/
https://ncbi.nlm.nih.gov/pubmed/7684215
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