Diarylsulfones, a new chemical class of nonnucleoside antiviral inhibitors of human immunodeficiency virus type 1 reverse transcriptase.

A series of variously substituted diarylsulfones and related derivatives were found to prevent human immunodeficiency virus type 1 (HIV-1) replication and HIV-1-induced cell killing in vitro. One of the more potent derivatives, 2-nitrophenyl phenyl sulfone (NPPS), completely protected human CEM-SS l...

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Publicado en:	Antimicrob Agents Chemother
Principais autores:	McMahon, J B, Gulakowski, R J, Weislow, O S, Schultz, R J, Narayanan, V L, Clanton, D J, Pedemonte, R, Wassmundt, F W, Buckheit, R W, Decker, W D
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187752/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7684215/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.4.754
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