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Cdc13 Telomere Capping Decreases Mec1 Association but Does Not Affect Tel1 Association with DNA Ends

Chromosome ends, known as telomeres, have to be distinguished from DNA breaks that activate DNA damage checkpoint. Two large protein kinases, ataxia-teleangiectasia mutated (ATM) and ATM-Rad3-related (ATR), control not only checkpoint activation but also telomere length. In budding yeast, Mec1 and T...

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Autors principals: Hirano, Yukinori, Sugimoto, Katsunori
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877102/
https://ncbi.nlm.nih.gov/pubmed/17377065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-12-1074
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