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Cdc13 Telomere Capping Decreases Mec1 Association but Does Not Affect Tel1 Association with DNA Ends

Chromosome ends, known as telomeres, have to be distinguished from DNA breaks that activate DNA damage checkpoint. Two large protein kinases, ataxia-teleangiectasia mutated (ATM) and ATM-Rad3-related (ATR), control not only checkpoint activation but also telomere length. In budding yeast, Mec1 and T...

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Bibliografische gegevens
Hoofdauteurs: Hirano, Yukinori, Sugimoto, Katsunori
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877102/
https://ncbi.nlm.nih.gov/pubmed/17377065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-12-1074
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