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ATR Homolog Mec1 Controls Association of DNA Polymerase ζ-Rev1 Complex with Regions near a Double-Strand Break

DNA polymerase zeta (Polζ) and Rev1 contribute to the bypassing of DNA lesions, termed translesion DNA synthesis (TLS) [1–3]. Polζ consists of two subunits, one encoded by REV3 (the catalytic subunit) and the other encoded by REV7. Rev1 acts as a deoxycytidyl transferase, inserting dCMP opposite les...

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Détails bibliographiques
Publié dans:Curr Biol
Auteurs principaux: Hirano, Yukinori, Sugimoto, Katsunori
Format: Artigo
Langue:Inglês
Publié: 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041964/
https://ncbi.nlm.nih.gov/pubmed/16546083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2006.01.063
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