Requirement of the Mre11 Complex and Exonuclease 1 for Activation of the Mec1 Signaling Pathway

The large protein kinases, ataxia-telangiectasia mutated (ATM) and ATM-Rad3-related (ATR), orchestrate DNA damage checkpoint pathways. In budding yeast, ATM and ATR homologs are encoded by TEL1 and MEC1, respectively. The Mre11 complex consists of two highly related proteins, Mre11 and Rad50, and a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Biol
Egile Nagusiak: Nakada, Daisuke, Hirano, Yukinori, Sugimoto, Katsunori
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2004
Gaiak:
DNA Dynamics and Chromosome Structure
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525484/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15509802/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.22.10016-10025.2004
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