Requirement of the Mre11 Complex and Exonuclease 1 for Activation of the Mec1 Signaling Pathway
The large protein kinases, ataxia-telangiectasia mutated (ATM) and ATM-Rad3-related (ATR), orchestrate DNA damage checkpoint pathways. In budding yeast, ATM and ATR homologs are encoded by TEL1 and MEC1, respectively. The Mre11 complex consists of two highly related proteins, Mre11 and Rad50, and a...
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| Publicat a: | Mol Cell Biol |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525484/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15509802/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.22.10016-10025.2004 |
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