Requirement of the Mre11 Complex and Exonuclease 1 for Activation of the Mec1 Signaling Pathway

The large protein kinases, ataxia-telangiectasia mutated (ATM) and ATM-Rad3-related (ATR), orchestrate DNA damage checkpoint pathways. In budding yeast, ATM and ATR homologs are encoded by TEL1 and MEC1, respectively. The Mre11 complex consists of two highly related proteins, Mre11 and Rad50, and a...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Nakada, Daisuke, Hirano, Yukinori, Sugimoto, Katsunori
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 2004
Fag:	DNA Dynamics and Chromosome Structure
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525484/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15509802/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.22.10016-10025.2004
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