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Rif1 and Rif2 inhibit localization of Tel1 to DNA ends

Chromosome ends, known as telomeres, have to be distinguished from DNA double-strand breaks (DSBs) that activate the DNA damage checkpoint. In budding yeast, the ATM homolog Tel1 associates preferentially with short telomeres and promotes telomere addition. Here we show that the telomeric proteins R...

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Bibliografische gegevens
Hoofdauteurs: Hirano, Yukinori, Fukunaga, Kenzo, Sugimoto, Katsunori
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662776/
https://ncbi.nlm.nih.gov/pubmed/19217405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.12.027
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