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Rif1 and Rif2 inhibit localization of Tel1 to DNA ends

Chromosome ends, known as telomeres, have to be distinguished from DNA double-strand breaks (DSBs) that activate the DNA damage checkpoint. In budding yeast, the ATM homolog Tel1 associates preferentially with short telomeres and promotes telomere addition. Here we show that the telomeric proteins R...

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Main Authors: Hirano, Yukinori, Fukunaga, Kenzo, Sugimoto, Katsunori
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662776/
https://ncbi.nlm.nih.gov/pubmed/19217405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.12.027
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