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Comparative neurotoxicities of amphotericin B and its mono-methyl ester derivative in rats.

The intracisternal administration of amphotericin B (AmB) and its mono-methyl ester derivative (AME), via direct intraventricular injection (0.01 to 5 mg/ml, 6 microliters) in adult female Wistar rats, revealed that AmB was significantly more toxic than AME, as measured by weight loss, lethargy, dea...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Reuhl, K R, Vapiwala, M, Ryzlak, M T, Schaffner, C P
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1993
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187687/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8384812/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.3.419
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