Comparative neurotoxicities of amphotericin B and its mono-methyl ester derivative in rats.

The intracisternal administration of amphotericin B (AmB) and its mono-methyl ester derivative (AME), via direct intraventricular injection (0.01 to 5 mg/ml, 6 microliters) in adult female Wistar rats, revealed that AmB was significantly more toxic than AME, as measured by weight loss, lethargy, dea...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Reuhl, K R, Vapiwala, M, Ryzlak, M T, Schaffner, C P
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1993
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187687/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8384812/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.3.419
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