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Identification of Potential Therapeutic Drugs for Huntington's Disease using Caenorhabditis elegans

BACKGROUND: The prolonged time course of Huntington's disease (HD) neurodegeneration increases both the time and cost of testing potential therapeutic compounds in mammalian models. An alternative is to initially assess the efficacy of compounds in invertebrate models, reducing time of testing...

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Bibliografiska uppgifter
Huvudupphovsmän: Voisine, Cindy, Varma, Hemant, Walker, Nicola, Bates, Emily A., Stockwell, Brent R., Hart, Anne C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2007
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876812/
https://ncbi.nlm.nih.gov/pubmed/17551584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000504
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