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Identification of Potential Therapeutic Drugs for Huntington's Disease using Caenorhabditis elegans

BACKGROUND: The prolonged time course of Huntington's disease (HD) neurodegeneration increases both the time and cost of testing potential therapeutic compounds in mammalian models. An alternative is to initially assess the efficacy of compounds in invertebrate models, reducing time of testing...

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Bibliographic Details
Main Authors: Voisine, Cindy, Varma, Hemant, Walker, Nicola, Bates, Emily A., Stockwell, Brent R., Hart, Anne C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876812/
https://ncbi.nlm.nih.gov/pubmed/17551584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000504
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