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Inhibitors of metabolism rescue cell death in Huntington's disease models
Huntington's disease (HD) is a fatal inherited neurodegenerative disorder. HD is caused by polyglutamine expansions in the huntingtin (htt) protein that result in neuronal loss and contribute to HD pathology. The mechanisms of neuronal loss in HD are elusive, and there is no therapy to alleviat...
Tallennettuna:
| Päätekijät: | , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2007
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1964858/ https://ncbi.nlm.nih.gov/pubmed/17726098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704482104 |
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